SFB 1243 Cancer Evolution

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Metzler, Dirk

Prof. Dr. Dirk Metzler

Faculty of Biology, Ludwig-maximilians-Universität München


Fakultät für Biologie
Ludwig-Maximilians-Universität München
Großhaderner Str. 2
82152 Planegg-Martinsried

Phone: +49 (0)89 2180-74108

Website: Evolutionary Biology: Statistical Genetics Group
Website: Description for doctoral position available

Work group

A16 Population genetics of hematopoietic neoplasms

10 Major publications related to project

Staab P, Zhu S, Metzler D and Lunter G (2015). scrm: efficiently simulating long sequences using the approximated coalescent with recombination. Bioinformatics, 31, 1680-1682. Lyras DP and Metzler D (2014). ReformAlign: improved multiple sequence alignments using a profile-based meta-alignment approach. BMC Bioinformatics, 15, 265.

Wittmann MJ, Gabriel W and Metzler D (2014) Population genetic consequences of the Allee effect and the role of offspring-number variation. Genetics, 198, 311-320.

Mathew L, Rose L, Staab P and Metzler D (2013). Why to account for finite-sites in population genetic studies and how to do this with Jaatha 2.0. Ecology and Evolution, 3, 3647-3662.

Wittmann MJ, Hutzenthaler M, Gabriel W and Metzler D (2013). Ecological and genetic effects of introduced species on their native competitors. Theor Popul Biol., 84, 25-35.

Doose G and Metzler D (2012). Bayesian sampling of evolutionarily conserved RNA secondary structures with pseudoknots. Bioinformatics, 28, 2242-2248.

Hoffmann D, Hutzenthaler M, Seebach J, Panning M, Umgelter A, Menzel H, Protzer U and Metzler D (2012). Norovirus GII.4 and GII.7 Capsid Sequences Undergo Positive Selection in Chronically Infected Patients. Infect Genet Evol, 12, 461-466.

Naduvilezhath L, Rose LE and Metzler D (2011). Jaatha: a fast composite-likelihood approach to estimate demographic parameters. Mol Ecol., 20, 2709-2723.

Brune V, Tiacci E, Pfeil I, Döring C, Eckerle S, van Noesel CJM, Klapper W, Falini B, von Heydebreck A, Metzler D, Bräuninger A, Hansmann ML and Küppers R (2008). Origin and pathogenesis of nodular lymphocyte-predominant Hodgkin lymphoma as revealed by global gene expression analysis. J Exp Med, 205, 2251-2268.

Metzler D (2003). Statistical Alignment based on fragment insertion and deletion models. Bioinformatics, 19, 490-499.