Responsibilities
Post-doctoral Researcher, Proteomics and Signal Transduction (Director: Matthias Mann)
Contact
Email:
jayavelu@biochem.mpg.de
Work group
Associated (since June 2018)
Selected Publications
Moloney JN, Jayavelu AK, Stanicka J, Roche SL, O'Brien RL, Scholl S, Böhmer FD, Cotter TG.Nuclear membrane-localised NOX4D generates pro-survival ROS in FLT3-ITD-expressing AML. Oncotarget. 2017 Nov 1;8(62):105440-105457.
Tsitsipatis D, Jayavelu AK, Müller JP, Bauer R, Schmidt-Arras D, Mahboobi S, Schnöder TM, Heidel F, Böhmer FD.Synergistic killing of FLT3ITD-positive AML cells by combined inhibition of tyrosine-kinase activity and N-glycosylation. Oncotarget. 2017 Apr 18;8(16):26613-26624
Jayavelu AK, Moloney JN, Cotter TG, Böhmer FD. NOX-driven ROS formation in cell transformation of FLT3-ITD-positive AML. Exp Hematol. 2016 Dec;44(12):1113-1122
Jayavelu AK, Müller JP, Bauer R, Böhmer SA, Lässig J, Cerny-Reiterer S, Sperr WR, Valent P, Maurer B, Moriggl R, Schörder K, Shah AM, Scholl S, Frey S, Fisher T, Heidel HF and Böhmer FD. NOX4-driven ROS formation mediates PTP inactivation and cell transformation in FLT3-ITD positive AML cells. Leukemia, 2016 Feb;30(2):473-83.
Abraham A, Varatharajan S, Karathedath S, Philip C, Lakshmi KM, Jayavelu AK, Mohanan E, Janet NB, Srivastava VM, Shaji RV, Zhang W, Abraham A, Viswabandya A, George B, Chandy M, Srivastava A, Mathews V, Balasubramanian P. RNA expression of genes involved in cytarabine metabolism and transport predicts cytarabine response in acute myeloid leukemia. Pharmacogenomics. 2015 Jul;16(8):877-90
Abraham A, Karathedath S, Kumaraswamy V, Jayavelu AK, Mani S, Srivastava WM, Zhang W, Zhou T, George B, Srivastava A, Mathews V, and Balasubramanian P. Novel NPM1 mutation in the 3'-untranslated region identified in two patients with acute myeloid leukemia. Leuk Lymphoma. 2014 Jun;55(6):1421-4.
Abraham A, Karathedath S, Varatharajan S, Markose P, Chendamarai E, Jayavelu AK, George B, Srivastava A, Mathews V, Balasubramanian P. ABCB6 RNA expression in leukemias--expression is low in acute promyelocytic leukemia and FLT3-ITD-positive acute myeloid leukemia. Ann Hematol. 2014 Mar;93(3):509-12.
Parihar M, Kumar JA, Sitaram U, Balasubramanian P, Abraham A, Viswabandya A, George B, Vikram M, Srivastava A, Srivastava VM. Cytogenetic analysis of acute myeloid leukemia with t(8;21) from a tertiary care center in India with correlation between clinicopathologic characteristics and molecular analysis. Leuk Lymphoma. 2012 Jan;53(1):103-9.
Parihar M, Kumar JA, Sitaram U, Balasubramanian P, Abraham A, Viswabandya A, George B, Vikram M, Srivastava A, Srivastava VM. Cytogenetic analysis of acute myeloid leukemia with t(8;21) from a tertiary care center in India with correlation between clinicopathologic characteristics and molecular analysis. Leuk Lymphoma. 2012 Jan;53(1):103-9.
Santhosh S, Dutta AK, Prasanna S, Joseph AJ, Ashok Kumar J and Kurian G. Cytokine Gene Polymorphisms in Irritable Bowel Syndrome in Indian Population. Trop Gastroenterol. 2010 Jan-Mar;31(1):30-3