SFB 1243 Cancer Evolution
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Schmidt-Supprian, Marc

Prof. Dr. Marc Schmidt-Supprian

Klinikum rechts der Isar, III. Medizinische Klinik, Technische Universität München

Contact

Klinikum rechts der Isar
III. Medizinische Klinik
Technische Universität München
Ismaninger Str. 22
81675 München

Phone: +49 (0)89 4140-4104

Website: TUM: Experimental Haematology

Work group

A12 Modeling molecular and cellular mechanisms of clonal evolution in indolent B cell lymphoma

10 Major publications related to project

Heger K*, Kober M, Rieß D, Drees C, de Vries I, Bertossi A, Roers A, Sixt M and Schmidt-Supprian M* (2015). A novel Cre recombinase reporter mouse strain facilitates selective and efficient infection of primary immune cells with adenoviral vectors. Eur J Immunol, 45, 1614-1620. *corresponding authors

Heger K, Fierens K, Vahl J C, Aszodi A, Peschke K, Schenten D, Hammad H, Beyaert R, Saur D, van Loo G, Roers A, Lambrecht B N, Kool M and Schmidt-Supprian M (2014). A20-deficient mast cells exacerbate inflammatory responses in vivo. PLoS Biol, 12, e1001762.

Vahl JC, Drees C, Heger K, Heink S, Fischer JC, Nedjic J, Ohkura N, Morikawa H, Poeck H, Schallenberg S, Rieß D, Hein MY, Buch T, Polic B, Schönle A, Zeiser R, Schmitt-Gräff A, Kretschmer K, Klein L, Korn T, Sakaguchi S and Schmidt-Supprian M (2014). Continuous T Cell Receptor Signals Maintain a Functional Regulatory T Cell Pool. Immunity, 41, 722-736.

Vahl J C, Heger K, Knies N, Hein M Y, Boon L, Yagita H, Polic B and Schmidt-Supprian M (2013). NKT cell-TCR expression activates conventional T cells in vivo, but is largely dispensable for mature NKT cell biology. PLoS Biol, 11, e1001589.

Chu Y, Soberon V, Glockner L, Beyaert R, Massoumi R, van Loo G, Krappmann D and Schmidt-Supprian M (2012). A20 and CYLD Do Not Share Significant Overlapping Functions during B Cell Development and Activation. J Immunol, 189, 4437-4443.

Bertossi A, Aichinger M, Sansonetti P, Lech M, Neff F, Pal M, Wunderlich F T, Anders H J, Klein L and Schmidt-Supprian M (2011). Loss of Roquin induces early death and immune deregulation but not autoimmunity. J Exp Med, 208, 1749-56.

Chu Y, Vahl J C, Kumar D, Heger K, Bertossi A, Wójtowicz E, Soberon V, Schenten D, Mack B, Reutelshöfer M, Beyaert R, Amann K, van Loo G and Schmidt-Supprian M (2011). B cells lacking the tumor suppressor TNFAIP3/A20 display impaired differentiation and hyperactivation and cause inflammation and autoimmunity in aged mice. Blood, 117, 2227-2236.

Derudder E, Cadera EJ, Vahl JC, Wang J, Fox CJ, Zha S, van Loo G, Pasparakis M, Schlissel MS, Schmidt-Supprian M