SFB 1243 Cancer Evolution
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Enard, Wolfgang

Prof. Dr. Wolfgang Enard

Faculty of Biology, Ludwig-maximilians-Universität München

Responsibilities

Scientific Coordinator for the IRTG

Contact

Fakultät für Biologie
Ludwig-Maximilians-Universität München
Großhaderner Str. 2
82152 Planegg-Martinsried

Phone: +49 (0)89 2180-74339

Website: Anthropology and Human Genetics

Work group

A14 Assessing genetic and epigenetic heterogeneity in hematopoietic neoplasms using single cell genomics

10 Major publications related to project

Schreiweis C, Bornschein U, Burguière E, Kerimoglu C, Schreiter S, Dannemann M, Goyal S, Rea E, French CA, Puliyadi R, Groszer M, Fisher SE, Mundry R, Winter C, Hevers W, Pääbo S, Enard W and Graybiel AM (2014). Humanized Foxp2 accelerates learning by enhancing transitions from declarative to procedural performance. PNAS, 111, 14253-14258.

Wunderlich S, Kircher M, Vieth B, Haase A, Merkert S, Beier J, Gohring G, Glage S, Schambach A, Curnow EC, Pääbo S, Martin U and Enard W (2014). Primate iPS cells as tools for evolutionary analyses. Stem Cell Research, 12, 622-629.

Fietz SA, Lachmann R, Brandl H, Kircher M, Samusik N, Schroder R, Lakshmanaperumal N, Henry I, Vogt J, Riehn A, Distler W, Nitsch R, Enard W, Pääbo S and Huttner W (2012). Transcriptomes of germinal zones of human and mouse fetal neocortex suggest a role of extracellular matrix in progenitor self-renewal. Proc Natl Acad Sci U S A, 109, 11836-11841.

Enard W, Gehre S, Hammerschmidt K, Holter SM, Blass T, Somel M, Bruckner MK, Schreiweis C, Winter C, Sohr R, Becker L, Wiebe V, Nickel B, Giger T, Muller U, Groszer M, Adler T, Aguilar A, Bolle I, Calzada-Wack J, Dalke C, Ehrhardt N, Favor J, Fuchs H, Gailus-Durner V, Hans W, Holzlwimmer G, Javaheri A, Kalaydjiev S, Kallnik M, Kling E, Kunder S, Mossbrugger I, Naton B, Racz I, Rathkolb B, Rozman J, Schrewe A, Busch DH, Graw J, Ivandic B, Klingenspor M, Klopstock T, Ollert M, Quintanilla-Martinez L, Schulz H, Wolf E, Wurst W, Zimmer A, Fisher SE, Morgenstern R, Arendt T, de Angelis MH, Fischer J, Schwarz J and Pääbo S (2009). A humanized version of Foxp2 affects cortico-basal ganglia circuits in mice. Cell, 137, 961-971.

Prufer K, Muetzel B, Do HH, Weiss G, Khaitovich P, Rahm E, Pääbo S, Lachmann M and Enard W (2007). FUNC: a package for detecting significant associations between gene sets and ontological annotations. BMC Bioinformatics, 8, 41.

Timpson N, Heron J, Smith GD and Enard W (2007). Comment on papers by Evans et al. and Mekel-Bobrov et al. on Evidence for Positive Selection of MCPH1 and ASPM. Science, 317, 1036.

Khaitovich P, Hellmann I, Enard W, Nowick K, Leinweber M, Franz H, Weiss G, Lachmann M and Pääbo S (2005). Parallel patterns of evolution in the genomes and transcriptomes of humans and chimpanzees. Science, 309, 1850-1854.

Mikkelsen T, Hillier LW, Eichler E, Zody MC, Jaffe DB, Yang SP, Enard W, Hellmann I, Lindblad-Toh K, Altheide TK, Archidiacono N, Bork P, Butler J, Chang JL, Cheng Z, Chinwalla AT, deJong P, Delehaunty KD, Fronick CC, Fulton LL, Gilad Y, Glusman G, Gnerre S, Graves TA, Hayakawa T, Hayden KE, Huang X, Ji H, Kent WJ, King MC, Kulbokas EJ 3rd, Lee MK, Liu G, Lopez-Otin C, Makova KD, Man O, Mardis ER, Mauceli E, Miner TL, Nash WE, Nelson JO, Pääbo S, Patterson NJ, Poh CS, Pollard KS, Prüfer K, Puente XS, Reich D, Rocchi M, Rosenbloom K, Ruvolo M, Richter DJ, Schaffner SF, Smit AFA, Smith SM, Suyama M, Taylor J, Torrents D, Tuzun E, Varki A, Velasco G, Ventura M, Wallis JW, Wend MC, Wilson RK, Lander E and Waterston R (2005). Initial sequence of the chimpanzee genome and comparison with the human genome. Nature, 437, 69-87.

Enard W, Khaitovich P, Klose J, Zöllner S, Heissig F, Giavalisco P, Nieselt-Struwe K, Muchmore E, Varki A, Ravid R, Doxiadis GM, Bontrop RE and Pääbo S (2002). Intra- and interspecific variation in primate gene expression patterns. Science, 296, 340-343.

Enard W, Przeworski M, Fisher SE, Lai CS, Wiebe V, Kitano T, Monaco AP and Pääbo S (2002). Molecular evolution of FOXP2, a gene involved in speech and language. Nature, 418, 869-872.